Case memo Essay Example | Topics and Well Written Essays - 1500 words

Case memo - Essay Example To evaluate the suitability of the new idea, White Appliances limited needs to consider the SWOT analysis for this case objectively. A SWOT analysis will be a useful technique that the company can use to determine its strengths, weaknesses, opportunities, and threats before considering the new venture. The technique will enable White Appliances to determine or identify a sustainable niche in the competitive global market. Using the SWOT analysis the company will be able to determine strategies that will make it stand out from its competitors. As a manager of the White Appliances limited, the company has adequate strength to penetrate and establish itself in the new Indian market. The company’s strengths are determined by what the company can do better than its competitor and factors that enable the company to stand out from its competitors. To begin with, White Appliances produces its microwaves from both its Asian and American manufacturing lines. The company markets its microwaves mainly in the American and European markets. Having two manufacturing locations for microwaves will enable the company to penetrate and sustain the Indian market. The company also needs to sustain its old markets while it searches for a new markets, the company can therefore decide to use its Asian production units to concentrate on the new market while the American production unit concentrates on the existing markets. White Appliances has marketed its products successfully in major European and American markets. This implies that the company has a good and reliable market that it can turn to incase the new venture prove to be unpromising. Being able to control the European and American markets has also enabled the company to acquire adequate profits that can be applied in any expansion measure undertaken by the company. The ability to control the American

Biographical Interpretation Works In Relation Essay Example for Free

Biographical Interpretation Works In Relation Essay Many literary works come across as hard for explanation, its been a problem since literature has been a main stay in society. Over time many styles of interpretation have been both approached and adapted by readers and critics alike. One of the most popular is the biographical interpretation. This is when a reader makes use of details regarding the life, times and works of an author as a means of solving interpretive problems. The biographical interpretation is a very good way to get inside the readers head because the past, and your past experiences are what shape your mind as it matures over time, even the smallest experience can make a decent sized impact on ones thought process. Mark Twain is a good example of an author that has been analyzed, possibly even over analyzed. By every angle he has been looked at, most notably for his works on The Adventures of Tom Sawyer and The Adventures of Huckleberry Finn. If you were to read his book The Adventures of Huckleberry Finn without taking a look at any biographical pieces about Mark Twain you would undoubtedly not get as much out of the novel as you would in contrast, if you were to read the biography. To prove the point the help of the semi-biographical essay The Life of Samuel Clemens and the Reception of Huckleberry Finn and The Adventures of Huckleberry Finn will be called upon throughout the essay. At the beginning of the biographical essay there is an excellent explanation of the personal side of Twain the only clear picture is that Twain was a man of paradox (pg. 19). The reason this excerpt fits the topic of biographical interpretation is because one key word within that quote, that key word being paradox. A paradox is a statement that seems contrary to common sense and yet is perhaps true. With The Adventures of Huckleberry Finn being the novel that we are taking a look at in contrast to the biographical side of Mark Twain this word, paradox, fits perfectly since there are paradoxes running throughout the novel. A good example of a paradox in the novel is from the mouth of Huck Finn himself: When it was dark I set by my campfire smoking, and feeling pretty satisfied; but by-and-by it got sort of lonesome, and so I went and set on the bank†¦ and counted the stars and drift-logs and rafts that come down, and then went to bed; there aint no better way to put in time when you are lonesome; you  cant stay so, you soon get over it. (Pg. 62) The paradox that has been spoken by Huckleberry is that depression and lonesomeness can be slept away. Which when first heard can be looked over and seen as straight out nonsense. However if it is thought about closely most people that are depressed can be get a quick fix from what makes them depressed by sleeping through it as much as they can, sort of like sleep and relaxation was the drug of its time. It may sound inconceivable now, but in the era that The Adventures of Huckleberry Finn was penned the idea of sleeping, or rather lounging around for days was not that inconceivable because they did not live the busy lifestyle in which we live in current time. This is just one of many paradoxes throughout the book that reflect the author in a great way due to the fact that he was known as a living paradox because of the way he lived his life. For a man that made money out of writing about adventures of rafting down the Mississippi and barely getting by money wise seem so interesting. But grew up living in Connecticut for a good amount of time in his life and also seeking to be filthy rich, and have no worries is most likely the biggest paradox of his life. Another way that the book of The Adventures of Huckleberry Finn can be looked at from a biographical perspective and make sense is the fact that the main characters in the novel have a very similar background as to which they grew up in. In a paragraph written by an African American professor of eastern studies and a writer of African-American folktales and poetry. A man by the name of Julius Lester speaks of the relationship between Huck, Tom, and Mark Twain himself in a very unique manner. Just after he speaks of how he does not recollect ever reading the writings of Mark Twain, but then says something to the effect of what American child hasnt read the tales of Huck and Tom so maybe he has, but the literature was not that significant to his life. What Lester has to say is something that most people taking the biographical interpretation approach should use as an approach to all authors in relation to the characters they write of: I do have an emotional memory of going to Hannibal, Missouri with my parents when I was eight or nine, and visiting the two-story frame house where Mark Twain lived as a boy-where Huck and Tom lived as boys. (Pg. 341, Morality and Adventures of Huckleberry Finn) This is a great comment because when you take a novel and  try and put a biographical interpretation onto that novel you need to take a very close look at the characters and their relation to the author. That is the mainstay of the biographical interpretation, how the characters are at all a parallel to the author. With Mark Twain himself growing up for part of his life on the Mississippi it gave him great knowledge of what he was talking about, and it gave him the roots of the characters that are now notable American icons. Him having the knowledge of the Mississippi, and of southern life in America at that time influenced the characters and the novel infinitely. Whether it is a satirical look at the way American life was at that time is a whole different essay. With all of this in mind it can be said that he sure lived the life of Huck and Tom whether it be on a lower level, or a parallel these characters and Mark Twain are one in the same. These are only a few examples of how the biographical interpretation of a novel is a very reliable approach to analyzing literature as long as you know that the biographical information is accurate. Doing this will also make the novel much more enjoyable because if you read the biographical essay, paragraph, novel, etc. Then you will be able to go along the book and be able to not look down upon the book, but look more for the reason that that author had said what he said, and what he really meant by it. It is about looking from the inside and looking out at the novel for the reasons behind what was said, instead of looking into the novel for the reasons to not read the book altogether

Tale of Two Cities Analys :: essays papers

Tale of Two Cities Analys Government has been an essential part to any civilization for as long as human kind has existed. People who disagree with the government have also existed for just as long. Whether the the government was so simple that the leader was the strongest in the tribe, or whether the government was so complex that it involved thousands of people to make one decision, it always was challenged and eventually changed. The means of change are quite diverse. Assassination, protests, war, petitions, and more are amongst the large list of means for governmental reform. Revolution has also been a frequent method to try to achieve the desired change. Revolutions have made profound impacts in history, for both the better and for the worse. Charles Dickens is among those who believe revolution is not a efficient means for change of government, or social reform. His classic novel, A Tale Of Two Cities, clearly and profoundly shows the negative impacts of revolting against the government, to the ! reader. He also shows the reader that there is a better way to improve the government. That better way is illustrated through Sydney Carton. He not only becomes an unexpected hero in A Tale Of Two Cities, but he also symbolizes Charles Dickens solution to achieving social reform. Sydney Carton first entered the story as a lonely man. Appearing rather insecure and having low self esteem, his role in the story was unknown to the reader. He seemed to only be focused on helping others. One late night with his colleague, Mr. Stryver, Cartons basically pathetic demeanor was confronted, ^Carton, addressed his friend... ^your way is, and always was, a lame way. You summon no energy and purpose. (Dickens, A Tale Of Two Cities, 95). Then later that night , Climbing into a high chamber in a well of houses, he threw himself down in his clothes on a neglected bed, and its pillow was wet with wasted tears (97). Both are examples of Cartons character. Most view him as a loser. Mr. Stryver, with the assistance of a little alcohol, clearly made that point, and sadly enough Carton realized it. At that moment he finally realized who he was becoming, and it depressed him beyond words. At that moment a new Carton emerged. This new Carton was someone who cared! for others. He wanted people to think that his actions were motivated by simply wanting to make a difference in the lives of those he cared for. One person he deeply cared for was Lucie Manette. She eventually became his motivation to change and renew his own life.

Parkinsons Disease

PD normally affects people over the age of 50. It becomes more common with increasing age. ‘About 5 in 1,000 people in their 60s and about 40 in 1,000 people in their 80s have PD'1. It affects both men and women but is a little more common in men. PD is not usually inherited, and can affect anyone. However, genetic factors may be important in the small number of people who develop the disease before the age of 50. PD therefore affects a lot of people in the UK and I have chosen this topic so I have a greater understanding of what they go through and how we can help those affected. Background: Biology of Parkinson's disease? Parkinson's disease is a chronic disorder of part of the brain called the substantia nigra. It mainly affects the way the brain co-ordinates the movements of the muscles in various parts of the body. This area of the brain sends messages down nerves in the spinal cord to help control the muscles of the body. Messages are passed between brain cells, nerves and muscles by chemicals called neurotransmitters. Dopamine is the main neurotransmitter that is made by the brain cells in the substantia nigra1.Muscular System: Muscle Metabolism In PD, cells in the substantia nigra are damaged and die. The cause is unknown. Over time, more and more cells become damaged and die. The more cells that are damaged the less dopamine is produced. The reduction of cells and the low level of dopamine in the cells in this part of the brain causes nerve messages to the muscles to become slowed and abnormal1. In the long term PD will ultimately lead to death. Causes We are still unsure of the causes of PD but here are the most likely and most talked about suggestions: 1. The hereditary form of PD occurs in fifteen per cent of cases2. The genes affected help clear nerve cells of excess proteins. Scientists are not sure but it is thought that when the ‘production process for protein manufacture breaks down, little clumps of ill-formed proteins begin to accumulate in cell' 17, causing cell death. Tests carried out on rats using rotenone imply that pesticides and toxins may lead to PD. The rats experienced shaking and a loss of muscle control as well as developing Lewy bodies (spherical lumps found in dying brain cells), which are commonly associated with Parkinson's disease. However, researchers are yet to find evidence for any definitive link to a particular toxin or drug in humans. 2. There seems to be a link between variants of the mitochondrial genes and PD. The Parkinson's Disease Research Agenda states that â€Å"mitochondrial dysfunction has numerous consequences, including energetic failure, generation of reactive oxygen species, disregulation of calcium homeostasis and induction of apoptosis, each of which may be important in Parkinson's disease†3. 3. High concentrations of free-radicals in the body and a lack of antioxidants. Free radicals damage cells and if too many dopamine-producing cells were damaged then this could lead to PD. Antioxidants prevent the production of free radicals and repair damage done by them. Symptoms and effects There is no easy test to diagnose PD, so it is diagnosed by ruling out other diseases and looking for the classic symptoms: * Slowness of movement (bradykinesia)1. It will become more of an effort to walk or get out bed. People may just think they are getting old and it is not till other symptoms develop that you may think about PD. * Stiffness of muscles (rigidity) and muscles may feel tenser. Also, your arms do not tend to swing as much when you walk. * Shaking (tremor) is common, but does not always occur. It normally affects the fingers, thumbs, hands, and arms, but can affect other parts of the body. It is most noticeable when you are resting and may become worse when you are anxious or emotional. It's generally less obvious when you use your hand to do something such as picking up an object or writing. Symptoms will tend to get worse and worse and as the disease develops. Some other symptoms may develop due to problems with the way affected brain cells and nerves control the muscles. These include: * Fewer facial expressions such as smiling or frowning. Less blinking. * Difficulty with fine movements such as tying shoe laces or buttoning shirts. * Difficulty with writing (handwriting tends to become smaller), balance and posture and swallowing. * Speech may become slow and monotonous. * Tiredness aches and pains. As PD gets really bad, symptoms such as the following might develop, dependant on the individual: * Constipation- †PD prevents the proper transmission of the neurological messages that tell the rectal sphincter muscles to open†7 * Hallucinations (seeing, hearing or smelling things that are not real) * Sweating- PD can affect the autonomic nervous system8 that controls the autonomic functions (functions done automatically by the brain and body without conscious thought) such as sweating, breathing etc. * Difficulties with sleeping * Weight loss- there is a generally decreased appetite associated with PD. This may largely be due to swallowing difficulties and other gastrointestinal disturbances8 * Pain * Depression & Anxiety- anxiety disorders occur in up to 40% of patients with Parkinson's disease (PD)9. The article states †Current evidence suggests that anxiety may not be a psychological reaction to the illness but rather may be linked to specific neurobiological processes accompanying PD.† * Problems with controlling impulses (for example compulsive eating, shopping or gambling) Most people will only suffer form a few of these symptoms and which ones will get worse and the speed at which they get worse varies hugely from person to person. Some rare brain diseases can have very similar symptoms in which case a specialist brain scan can often be used to distinguish between them. The Treatments At the moment there is no cure for PD and most treatments simply have the job of relieving symptoms. 1. Drugs Intro: there are two main types of drug used in PD treatment. Firstly, drugs that target the neurotransmitter systems (e.g. dopamine) or secondly drugs that are designed to interfere with steps in the neurodegenerative processes (they may aim to sustain nerve cells or tackle the issue of free radicals). Drugs are cheap and effective, especially in relieving symptoms but show little potential as a full cure to the disease. Most also need to be taken daily for the remainder of a patients lifetime. Many drugs may have minor side affects. Some side affects have social impacts such as mood swings or may not allow the user to fly or travel to certain places. Dopaminergic Agents- use to activate the production or use of Dopamine. Levodopa- is an amino acid that is converted in the brain into dopamine. According to the WE MOVE website10 ‘Levodopa was introduced as a PD therapy in the 1960s, and remains the most effective therapy for motor symptoms' although there are many drugs that do a similar job such as Rasagiline. It reduces the effect of and helps control the symptoms of PD. Like most amino acids levodopa is absorbed into the blood stream through the wall of the intestines. Amino acids require a ‘transporter' to transfer them across the membrane of the intestines and into the blood stream. These transporters can only work at a certain rate and so diet is important. To much dietary protein can slow the transport of levodopa into the blood stream meaning the dose may be ineffective. Alternatively to avoid the competition with other amino acids, doses should be taken between meals. Levodopa has to cross from the blood stream into the brain using the same transport system again, making diet and timing doubly important. MAO-B Inhibitors- slow the breakdown of dopamine in the brain and aim to prevent or slow the death of neurons. ‘MAO is responsible for the mitochondrial metabolism of monoamine neurotransmitters, including dopamine and serotonin.'11 Ethical implications Some of the many ethical issues revolve around the decision to move from testing on artificial tissue (often grown from stem cells, which may in the future replace animal testing altogether. Stem cells, however create there own ethical issues) to animals, and further on the line, of animal testing to trails on human patients. The graph below shows the stages involved in developing a new drug and is taken from the MSD website (21/3/10): (http://www.msd.com.hk/health_info/drug_education/e_ddp_introduction.html) Animal testing is very closely regulated in the UK however many, often false, accusations of animal abuse have lead to darkened perceptions of animal testing in the public eye. Animal abuse is definitely a reality but ‘improved transparency, accountability and regulations'12 should reduce it happening and make sure those responsible are prosecuted. Unlike humans, animals are unable to consent to testing. It is forced upon them and often involves a certain amount of pain, stress, suffering and discomfort. Researchers will try to reduce this, possibly using anaesthetics although this can often interfere with the drug being tested so the animal may have to suffer the full amount of pain. Unfortunately, in PD, a number of animals are tested on normally starting with mice or rats before moving on to monkeys and finally human trails. Some people believe that animals like monkeys and most primates shouldn't be experimented upon as they aren't in the same plentiful supply that rats and mice are in, nor are they considered pests. However, for potentially dangerous drugs it is essential animals with a similar genetic make up (primates) are tested on to greatly reduce the risks in human clinical trails. Economics of drugs in PD As shown in figure 1.2 drug development requires a huge amount of research and testing and can take more than 10 years before a useable drug is created. This obviously requires a huge amount of investment and general drug development costs vary between 500 and 2,000 million dollars. R;D is often done by independent companies or government organizations. Most companies or organizations will link with universities to share information and facilities and hopefully quicken to process of discovering a new drug. ‘After approval, pharmaceutical companies have a short period of exclusivity before patents expire and other companies can market the same drugs as generics. This time is used to recoup the massive investment required to develop and launch a new drug. However, the companies must also continue to test their drugs and monitor the feedback from healthcare professionals in order to identify undiscovered side effects, risk factors and interactions.'13 Drug companies are some of the most profitable industries in the world and although a large amount of money is needed in research and development (R;D) only 1 in 5 dollars made is then invested in further research. Many companies spent nearly twice as much money on advertising and marketing than R;D and demand is so much higher than it needs to be that companies can afford to boost prices to maximise profit. Luckily with PD this becomes less of a problem as people are unlikely take and therefore buy drugs that are meant for PD when they don't actually need it. This is because the symptoms tend to be quite clear and drugs like levodopa are not readily available unless prescribed. Benefits to humans Drugs can have a massive impact on people suffering from PD and they aim to do a number of things: 1) Improve standards of living- by reducing the affects of PD and slowing the process of neurodegeneration it should allow the person suffering to do basic things (such as tying shoelaces, writing etc) more easily and for longer before they require full time medical care. This allows them to be more independent. 2) The use of drugs such as levodopa, in the long term, will reduce the affects of symptoms such as tiredness, aches and pains. Painkillers like amantadine will also be used for more short term relieve along side drugs like levodopa. This will simply make life less painful for a PD patient. 3) Drugs are the most well know and reliable of PD treatments. This reduces the risks of any unknowns or mistakes and far fewer mistakes will be made than in using other treatments. Risks to humans 1) Unfortunately Nausea and vomiting are common side effects of using levodopa that are due to the building up of dopamine in the bloodstream. The most serious and severe effect of this treatment is dyskinesias. ‘Dyskinesias are uncontrolled movements, including writhing, twitching, and shaking. Dyskinesias result from the combination of long-term levodopa use and continued neurodegeneration. They typically begin to develop in milder forms after 3 to 5 years of treatment, but are more severe after 5 to 10 years of treatment.'10 2) There is always risk of allergies when using drugs and for some unfortunate people drugs may do more damage than good. 3) Side affects of drugs vary from person to person and it is impossible to know beforehand how a certain drug will affect an individual. For some, side affects may be far worse than for others. 4) Dosages need to be got right and it is a common problem that people take to little and don't get the full benefit of the drug or take to much and suffer more/worse side affects. A massive overdose will likely lead to death. Alternative Cures? 2. Gene therapy- is still in early research stages and it is likely to be a while before this technique is actually used on humans. Like stem cells it has exciting potential to provide a future cure and avoid the ethical issues associated with stem cells. How it works? Gene therapy aims to introduce new and functioning genetic material into cells that have abnormal genes that are causing proteins (in the case of PD, dopamine) not to be created or created faulty. The genetic material can normally be inserted into the cells using viruses. ‘Some types of virus, such as retroviruses, integrate their genetic material (including the new gene) into a chromosome in the human cell. Other viruses, such as adenoviruses, introduce their DNA into the nucleus of the cell, but the DNA is not integrated into a chromosome.'13There is still much development needed as scientists are still unable to target specific cells and there is the potential threat of virus mutation which may cause even further problems. There is also major worry about the potential for gene therapy to be used to improve basic human traits such as height, intelligence etc. People could simply choice characteristics and this in many people's eyes could be used for the wrong reason. For example, this may be used to give some athletes a major advantage over others or possibly creating super humans. 3. Stem Cells I think stem cells have shown exciting potential and will hopefully provide a full time future cure for the disease. How they work? Stem cells are unspecialised cells that have the ability to develop into highly specialised cells like nerve cells. They can also self-renew, which means they are capable of replenishing themselves for long periods of time by dividing4. For Parkinson's disease it is hoped that large numbers of the brain cells that produce dopamine can be produced and inserted, through transplantation, into a patient's brain. Therefore, nerve messages to all parts of the body will be normal again. However, stem cells not been successfully used to cure PD yet and there are many problems facing researchers. Therefore stem cells are relatively useless for PD at the moment but may be able to provide an easy and affective cure in the future. Problems with the types of Stem cells There are three main types of stem cells: 1. Adult stem cells can come from Skin, Bone marrow, Brain, Blood vessels, Liver and Skeletal muscle. However, adult stem cells are found in such small quantities it is difficult to identify and isolate them in viable numbers. Because adult stem cells aren't as ‘young' as embryonic stem cells, they contain more DNA abnormalities acquired with age4. These can be caused by the environment, toxins or errors in DNA replication. Adult stem cells have limited potential because unlike embryonic stem cells they can not differentiate into any specialised cell in the body. 2. Cord blood cells are normally found in the umbilical cord and placenta after the cord is cut. One problem is the lack of cells obtained and these may not be enough relative to a patient's size. Cord blood cells generally take longer to grow, therefore completion of therapy will take longer. It obviously requires a pregnant woman to donate the cells. 3. Embryonic stem cells are found in human embryos and have a seemingly unlimited potential to develop into any cell in the human body. However they are surrounded by a number of ethical issues. Many people and especially religious group condemn the use of embryonic stem cells as they believe it is destroying a life. They believe it is immoral to save a life at the expense of another. However new developments in stem cells research means that Totipotent* stem cells can now be collected without the loss of embryo life: Somatic cell nuclear transfer (SCNT) – nucleus is removed from a somatic cell and is then implanted into a donor egg that has had its nucleus removed6. It divides just as normal before forming an embryo. Cells from the inner cell mass are extracted and cultured to provide embryonic stem cells but the technique destroys the embryo. Although the embryo is destroyed it is a created clone and so may not be considered the loss of new, individual life. Altered nuclear transfer (ANT), however, prevents an embryo from actually being created. The nucleus of the somatic cell is altered, or genetically reprogrammed, before being transferred into the egg. The alteration consequence is that the somatic cell DNA still produces stem cells but does not generate an embryo. Blastomere Extraction is performed on a two-day old embryo, following the division of the fertilized egg into eight blastomeres (cells). One blastomere is removed and can be triggered to divide and the resulting stem cells could still be used for research and disease treatment. The embryo, ‘now with only seven blastomeres can still be implanted into the mother and assuming no defect has been found these embryos will still grow into healthy babies'4. 1. Name of article: Parkinson's Disease Url: http://www.patient.co.uk/health/Parkinson's-Disease.htm Date accessed: 15/2/10 Evaluation: The article is certified as a reliable source of health and social care information. It certificate states- ‘The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest.' The article states that Parkinson's disease affects the part of the brain know as the substantia nigra. WE MOVE (Worldwide Education and Awareness for Movement Disorders- http://www.wemove.org/par/par_subn.html) states: ‘In PD, cells of the SN (substantia nigra) degenerate, and therefore can no longer produce adequate dopamine.' This information is further backed up on the Parkinson's Disease Research Agenda that states ‘cells that produce the neurotransmitter dopamine die in a small brain area called the substantia nigra.' As the information provided is backed by what I consider to be reliable resources I think that the i nformation on the website is also therefore reliable, but should be checked with other sources before being used. 2. Name of article: Possible Causes of Parkinson's Disease (PD) Url: http://www.healthtree.com/articles/parkinsons-disease/causes.php Date accessed: 20/2/10 3. Name: Parkinson's Disease Research Agenda URL: http://www.ninds.nih.gov/about_ninds/plans/nihparkinsons_agenda.htm#Parkinson Date accessed: 20/2/10 Evaluation: Parkinson's disease Research Agenda is written by the National Institute of Neurological Disorders and Stroke (NINDS). It primary aim is to †reduce the burden of neurological disease – a burden borne by every age group, by every segment of society, by people all over the world.† It is funded by the government so should provide no bias and the site aims to educate people about various neurological disorders including Parkinson's disease. It states â€Å"mitochondrial dysfunction has numerous consequences†¦ each of which may be important in Parkinson's disease.† This is also backed by an article: http://www.nature.com/nrneurol/journal/v6/n2/full/nrneurol.2009.221.html that states † dysfunctional energy metabolism might be a central element of the pathological process underlying the development of PD.† The site was last updated on the 25th of July 2008. As the site is run and updated by the government with no other purpose but to inform I think it can be used a very reliable source of information.

Deadly Feasts

Erica Dunyon Directed Readings Deadly Feasts by Richard Rhodes I have to admit, on the opening scene I was really skeptical about reading this book. I really have always hated the idea of cannibalism, so when I was reading and imagining this, in my mind one word came to my attention, â€Å"Disgusting! † Progression into the book, however, received my attention, and I continued forward. I enjoyed reading this book. It was very informative, easy to understand, and easy to read. I learned about various prion diseases and their effect on each species they infect.Deadly Feasts is about spongiform encephalopathies including Creutzfeldt-Jakob disease, Scrapies, Rida, Kuru, and mad cow disease. This book explains the relationships each spongiform disease has in common with each other, as well as their signs and symptoms. Mad cow disease and scrapies are quite similar to each other, and was endemic in Britain when this book was published. Another rare disease occurring in humans known as Creutzfeldt-Jakob disease has then been related to mad cow disease. Creutzfeldt-Jakob disease is one in which eats human brains. Kuru is thought to be another spongiform disease.Kuru was thought to be a result of sorcery. Initially when this disease was discovered, the belief was leaning toward this disease taking on a genetically transmissible role. After much research, it is known that it is a transmissible disease spread by the consumption of infected flesh. The extremely unusual thing about kuru, along with other spongiform encephalopathies, is that it lacks the presence of inflammation. Transmissible spongiform encephalopathies (TSEs) are also known as prion diseases. The infectious microbe in TSEs is a specific protein called prion protein.These prion proteins and proteins of the brain are extremely similar. This may be the reason these proteins are not detected by the immune system which is why they do not cause inflammation. These diseases are unique because they are impo ssible to kill. They have been exposed to virtually everything including, extreme temperatures and radiation, and still have the ability to infect and cause disease. Gajdusek believed that transmission of these spongiform encephalopathies was in the form of protein in diseased dead animals, including sheep and cattle that were fed to other cattle.Rhodes refers to a concept known as industrial cannibalism. This means that the supplements were made from dead cows. Despite the fact that cattle were coming down with a disease that decreases the cow population, supplements were still made with the remaining’s of diseased cattle and fed to other cattle. Transmission of this disease can occur months or even up to decades because the disease can incubate for the allotted time. Britain was responsible for the initiation of research in this epidemic group of diseases. Britain did not inform the public in regards to this disease.They also bought diseased animals for half of the market v alue. The British government banned individuals from feeding animal waste to other animals, in 1989 to limit the spread of these diseases. In addition to limitting the transmission of these diseases, as a safety measure, the FDA prevented industries from feeding cattle protein from dead sheep, cattle, and other susceptible diseased animals. Europe still has increasing cases of the disease, which it infects many various herds and species of animals, supporting that the epidemic disease is able to spread across the species barrier The British government, by making the wrong public health choices, has conducted a frightening natural experiment, allowing a lethal disease agent to spread through the human food supply, exposing the entire British population. † (Rhodes 97) America is trying to prevent the spread of spongiform disease transmission from Britain to the U. S. by manufacturing our own beef and meat products. Unfortunately, it would not be known if the disease has affected our population until it is a point when it might be too late. TSE’s are essentially unidentifiable until they progress to the point of brain damage. † (Rhodes 97) Spongiform diseases are still a known problem in the world, and the protection we give ourselves, or lack of protection is an issue brought up by Rhodes. Rhodes refers that spongiform diseases might be Britain's †new Black Death. † He states that the transmissible spongiform encephalopathies are public health problems and not only clinical. Transmission is controlled by actions of both social and institutional aspects.The term the â€Å"new Black Death† refers to the ease of the transmission of the disease. If the plan for eradication is not carefully planned and executed, transmissible spongiform encephalopathies can be a serious epidemically known disease that can cause many deaths. In conclusion, I recommend Deadly Feasts to all individuals, not necessarily limited to only those interest ed in microbiology. This book gives insight on a former, and always possible, group of diseases that can become epidemic at any time. I believe knowledge is power, so knowing about these diseases only contributes to public safety.